Science and Clinical Papers

Deuterium Depleted Water – General Information

“Naturally occurring deuterium is essential for the normal growth rate of cells”

“Structural homologies between phenformin, lipitor and gleevec aim the same metabolic oncotarget in leukemia and melanoma”

“Serine Oxidation via Glycine Cleavage (SOGC) Continues its Emergence as a Hallmark of Defective Mitochondria”

“Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle”

 

Deuterium Depleted Water in Cancer Treatment

“Deuterium Has a Key Role in Tumour Development – A New Submolecular Regulatory System”

“Deuterium Depleted Water Effects on Survival of Lung Cancer Patients and Expression of Kras, Bcl2, and Myc Genes in Mouse Lung”

“Pre-Clinical and Clinical Data Confirm the Anticancer Effect of Deuterium Depletion”

“A Retrospective Evaluation of the Effects of Deuterium Depleted Water Consumption on 4 Patients with Brain Metastases from Lung Cancer”

“A retrospective study of survival in breast cancer patients undergoing deuterium depletion in addition to conventional therapies”

“Deuterium Depletion May Delay the Progression of Prostate Cancer”

“Fumarate hydratase and deuterium depletion control oncogenesis via NADPH-dependent reductive synthesis”

“Fumarate hydratase and deuterium depletion control oncogenesis via NADPH-dependent reductive synthesis: mitochondrial matrix water, DNA deuteration and epigenetic events.”

 

Deuterium Depleted Water in Depression and Anxiety

“Deuterium content of water increases depression susceptibility: The potential role of a serotonin-related mechanism”

 

Deuterium Depleted Water in Anti-Aging

“Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model”

 

Deuterium Depleted Food (Ketogenic Diets) – General Information

“What to eat or what not to eat – that is still the question”

“Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death”

“Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects”

“Low-carbohydrate nutrition and metabolism”

“The Modified Atkins Diet”

Deuterium Depleted Food (Ketogenic Diets) in Disease Treatment

 

Amyotrophic Lateral Sclerosis – ALS

“A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis”

 

Cancer

“Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial”

“The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma”

“The Restricted Ketogenic Diet: An Alternative Treatment Strategy for Glioblastoma Multiforme”

“Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report”

“Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer”

“Fasting and Cancer Treatment in Humans: A Case series report”

 

Diabetes

“Type I diabetes and epilepsy: Efficacy and safety of the ketogenic diet”

“Type 1 diabetes mellitus successfully managed with the paleolithic ketogenic diet.”

“Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes”

 

Epilepsy

“The Ketogenic and Atkins Diets: Recipes for Seizure Control”

“Ketone bodies in epilepsy”

 

Polycystic Ovary Syndrome

“The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: A pilot study”

 

Weight Loss

“Weight Gain,Metabolic Syndrome, and Breast Cancer Recurrence: Are Dietary Recommendations Supported by the Data?”

“Long-term effects of a ketogenic diet in obese patients”

Mitochondria and Health

“Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression”

“Mitochondrial Dysfunction in Depression”

“Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia: Possible Interactions with Cellular Processes”

“The Rise of Mitochondria in Medicine”

“Mitoproteomics: Tackling Mitochondrial Dysfunction in Human Disease”

“Mitochondrial morphology in metabolic diseases”

 

Mitochondria and Cancer

“Mitochondrial Determinants of Cancer Health Disparities”

“Mitochondria and Cancer”

“Mitochondria and cancer chemoresistance”

“Restoration of mitochondria function as a target for cancer therapy”

“Targeting cancer cell mitochondria as a therapeutic approach”

“Mitochondrial metabolism and cancer”